As an industry leader in lipid delivery technology, Scindy Pharmaceutical leverages its proprietary advanced lipid material platform to achieve breakthrough applications of LNP (Lipid Nanoparticle) technology. We proudly introduce a series of innovative cell transfection products based on LNP technology, marking a new era of precise and efficient RNA delivery by systematically applying LNP technology to in vitro transfection.

The NeoLNP™ RNA Transfection Kit for Common Cells (SDR8006) is designed for common cell lines, offering an efficient and reliable transfection solution that simplifies and accelerates RNA research in these cells.

NeoLNP™ SDR8006: Superior RNA Delivery Performance, Broadly Applicable to Common Cells

High Cell Expression: SDR8006 achieves efficient intracellular delivery through unique transmembrane transport and endosomal escape mechanisms, easily achieving transfection efficiencies above 90%.

Compatible with Various RNA Types: Suitable for transfecting mRNA, siRNA, gRNA, saRNA, circRNA, and other RNA types.

Messenger RNA (mRNA):

* Using a 24-well plate, transfect with eGFP mRNA, followed by fluorescence imaging and flow cytometry analysis after 24 hours.

Small Interfering RNA (siRNA) - Cellular Uptake Efficiency:

* Transfect with 30nM Cy3-labeled siRNA per well, followed by fluorescence imaging after 6 hours.

Small Interfering RNA (siRNA) - Gene Silencing Efficiency

* Transfect with 30nM GAPDH siRNA per well, followed by qPCR analysis after 48 hours to measure GAPDH mRNA relative expression levels.

Circular RNA (circRNA):

* Using a 96-well plate, transfect with 100ng eGFP circRNA per well, followed by fluorescence imaging after 24 hours.

Self-Amplifying RNA (saRNA):

* Using a 96-well plate, transfect with 100ng eGFP saRNA per well, followed by fluorescence imaging after 24 hours.

Extremely Low Cytotoxicity: Utilizes biodegradable materials, free of ethanol, with minimal impact on cells, reducing experimental bias. After transfecting 30nM GAPDH siRNA into 293T cells, cell proliferation activity is assessed using a CCK-8 kit after 24 hours.

Broad Cell Compatibility: Successfully validated in over 100 cell types, including A549, Capan-2, and HEK293, with most achieving transfection efficiencies exceeding 90%. SDR8006 far surpasses industry standards.

NeoLNP™ Simple and User-Friendly RNA-LNP Encapsulation Solution The NeoLNP™

Transfection Kit offers an innovative RNA-LNP encapsulation solution. Compared to traditional methods, NeoLNP™ requires no complex equipment, achieving zero-loss RNA encapsulation through a simple one-step mixing process, significantly reducing preparation time (1 minute vs. 10 hours). This technology overcomes the technical barriers of traditional LNP preparation, delivering optimized, standardized LNP formulations to researchers, providing a new experience for RNA transfection.